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It isn't surprising that considerable attention is directed toward carefully choosing solvents for NMR experiments. Today, solvents must provide an effective medium in which to dissolve a sample to the required concentration and filling-factor . . . must contribute no interfering resonances . . . and must provide a lock signal to assure spectrometer stability. This presents stringent challenges for manufacturers of NMR solvents when added to the obvious need for chemical purity.

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